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PFBH offers interventional psychiatry services in Charlotte, including TMS and Spravato® for individuals seeking alternatives to traditional treatment. These advanced therapies provide new options for patients working toward meaningful and lasting mental health improvement.
SPRAVATO® (Esketamine)
SPRAVATO® Treatment for Depression in Charlotte, NC | Interventional Psychiatry at PFBH
SPRAVATO® (esketamine) is now available at Pediatric and Family Behavioral Health in Charlotte, NC—offering new hope for adults living with Treatment-Resistant Depression (TRD) and Major Depressive Disorder (MDD).
SPRAVATO® is an FDA-approved, evidence-based treatment provided through our Interventional Psychiatry services in Charlotte, administered under medical supervision in a safe, supportive outpatient setting. Designed for individuals who have not experienced adequate relief from traditional antidepressants, SPRAVATO® works differently by targeting NMDA receptors in the brain to help rapidly reduce depressive symptoms.
At Pediatric and Family Behavioral Health, our experienced psychiatric team develops personalized care plans that integrate SPRAVATO® with comprehensive medication management and therapeutic support, helping patients move toward meaningful, lasting improvement.
SPRAVATO® is covered by many major insurance plans, and our team assists with benefits verification and prior authorization to help make treatment accessible.
Who Is a Candidate for SPRAVATO®?
You may be a candidate for SPRAVATO® treatment if you:
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Have been diagnosed with Major Depressive Disorder or Treatment-Resistant Depression
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Have tried two or more antidepressant medications without sufficient improvement
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Continue to experience moderate to severe depressive symptoms
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Are seeking advanced, brain-based depression treatment options
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Can participate in in-office monitored treatment sessions
Our Charlotte community now has access to this innovative interventional psychiatry option, delivered with compassionate, evidence-based care. If you or a loved one is struggling with depression that has not responded to traditional treatments, the PFBH team is here to help explore whether SPRAVATO® may be right for you.
Partnering with Families for a Brighter Tomorrow
About SPRAVATO®
SPRAVATO® (esketamine) is a groundbreaking prescription nasal spray designed to help adults struggling with treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts or actions. Unlike traditional antidepressants, SPRAVATO® works rapidly to relieve symptoms, offering hope to individuals who have not responded to other treatments.
Frequently Asked Questions (FAQs) About SPRAVATO®
Spravato is a derivative of ketamine, a well-known anesthetic, and functions by targeting glutamate receptors in the brain. This unique mechanism helps restore synaptic connections, which can improve mood and cognitive function faster than conventional antidepressants.
Spravato is specifically approved for:
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Treatment-resistant depression (TRD): For individuals who have tried at least two different antidepressants without success.
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Major depressive disorder (MDD) with suicidal thoughts or actions: A critical option for those experiencing severe, urgent symptoms of depression.
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Spravato is administered as a nasal spray under the supervision of a healthcare provider. Treatment sessions take place in a certified medical facility, where patients are monitored for at least two hours to ensure safety. Spravato is typically used alongside an oral antidepressant for the best results.
For Providers:
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Send a referral at the following fax (877)-319-1017
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Email a referral at intake@pfbhnc.com
For Patients:
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Call (980)-237-4766 ext 103
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Email us at intake@pfbhnc.com to inquire about our program
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SPRAVATO® offers the freedom to choose your treatment approach
Start with 56 mg or 84 mg, alone or in combination with an oral AD, and an individualized dosing schedule-
If clinically warranted, you may start a patient on SPRAVATO® alone — without the need to combine it with an oral AD
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SPRAVATO® now offers more flexibility in treatment approach, dosing, and post-induction frequency
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Evidence of therapeutic benefit should be evaluated at the end of the induction phase to determine need for continued treatment
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Why Trust PFBHNC for Your SPRAVATO® Treatment?
At PFBH, we understand that depression is a deeply personal struggle, and finding the right treatment can be challenging. That’s why we offer SPRAVATO®, an innovative, fast-acting solution for individuals with treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts or actions.
Expert-Led Care
Our large team of experienced mental health professionals ensures that every SPRAVATO® session is safe, effective, and tailored to your unique needs. Pediatric and Family Behavioral Health delivers a higher standard of care through our integrated model combining psychiatry, therapy, and advanced interventional treatments like SPRAVATO® in one convenient, coordinated setting.
Comfortable & Supportive Environment
SPRAVATO® is administered in a calm, thoughtfully designed clinical setting where comfort meets medical oversight. Each session takes place in private or semi-private treatment rooms, with continuous monitoring by our trained clinical team to ensure safety and support throughout your visit. Our space is designed to feel welcoming and restorative so you can focus on healing.
Fast-Acting Relief for Depression
Traditional antidepressants can take weeks to show meaningful improvement, but SPRAVATO® works differently. Many patients experience relief from depressive symptoms within hours to days of the first dose. Clinical studies show that SPRAVATO®, when used with an oral antidepressant, produces rapid and significant improvements — with up to 70% of patients achieving a clinical response (≥ 50% reduction in symptoms) and around 40 to 50% reaching remission within the first month of treatment
Flexible After-Hours Appointments
We know that balancing work and mental health care can be difficult. That’s why PFBH offers after-hours SPRAVATO® appointments, making it easier for working professionals to get the treatment they need, without disrupting their busy schedules. Ask our team about our availability for late afternoon appointments on Wednesdays or Thursdays.
Starting in March 2026, schedule your Saturday morning appointments with us.
A Holistic & Comprehensive Approach
At PFBH, we combine SPRAVATO® with therapy, lifestyle recommendations, and ongoing support to help you achieve long-term success in managing depression.
Certified & Compliant Treatment Center
As a certified SPRAVATO®provider, PFBHNC adheres to all Risk Evaluation and Mitigation Strategy (REMS) program guidelines, ensuring that you receive treatment in a safe and controlled environment.
What Is Spravato?
Spravato (esketamine) is a groundbreaking prescription nasal spray designed to help adults struggling with treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts or actions. Unlike traditional antidepressants, Spravato works rapidly to relieve symptoms, offering hope to individuals who have not responded to other treatments.
How Spravato Works
Spravato is a derivative of ketamine, a well-known anesthetic, and functions by targeting glutamate receptors in the brain. This unique mechanism helps restore synaptic connections, which can improve mood and cognitive function faster than conventional antidepressants.
How Is Spravato Administered?
Spravato is administered as a nasal spray under the supervision of a healthcare provider. Treatment sessions take place in a certified medical facility, where patients are monitored for at least two hours to ensure safety. Spravato is typically used alongside an oral antidepressant for the best results.
How Is Spravato Administered?
Spravato is administered as a nasal spray under the supervision of a healthcare provider. Treatment sessions take place in a certified medical facility, where patients are monitored for at least two hours to ensure safety. Spravato is typically used alongside an oral antidepressant for the best results.
Why Choose Spravato at PFBHNC?
At PFBHNC, we understand that depression is a deeply personal struggle, and finding the right treatment can be challenging. That’s why we offer Spravato, an innovative, fast-acting solution for individuals with treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts or actions.
Why Trust PFBHNC for Your Spravato Treatment?
✅ Expert-Led Care
Our team of experienced mental health professionals ensures that every Spravato session is safe, effective, and tailored to your unique needs.
✅ Comfortable & Supportive Environment
Spravato is administered in a calm, supervised setting, where our staff closely monitors you throughout your session to ensure both safety and comfort.
✅ Fast-Acting Relief for Depression
Traditional antidepressants can take weeks to work, but Spravato has been shown to provide relief within hours to days, offering hope for those experiencing severe depression.
✅ Flexible After-Hours Appointments
We know that balancing work and mental health care can be difficult. That’s why PFBHNC offers after-hours Spravato appointments, making it easier for working professionals to get the treatment they need—without disrupting their busy schedules.
✅ A Holistic & Comprehensive Approach
At PFBHNC, we combine Spravato with therapy, lifestyle recommendations, and ongoing support to help you achieve long-term success in managing depression.
✅ Certified & Compliant Treatment Center
As a certified Spravato provider, PFBHNC adheres to all Risk Evaluation and Mitigation Strategy (REMS) program guidelines, ensuring that you receive treatment in a safe and controlled environment.
Is Spravato Right for You?
If you or a loved one is struggling with treatment-resistant depression, we’re here to help. With expert care, a supportive environment, and after-hours availability, PFBHNC makes it easier than ever to access this breakthrough treatment.